Boğaziçi CT3
Device Name / Brand / Model
• Name: 7T Preclinical Small-Animal MRI Scanner
• Brand: MRSolutions
• Model: MRS*DRYMAG 7017 (7 Tesla)
Overview
The MRSolutions MRS*DRYMAG 7017 7T preclinical MRI scanner, located at the Center for Targeted Therapy Technologies – Experimental Animal Imaging Unit, is suitable for in-vivo (live animals), ex-vivo (tissue samples), and other sample types (e.g., devices, chemical components). The ultra-high magnetic field strength (7T), combined with a small-bore gantry and dedicated small-animal RF coils, delivers high signal-to-noise ratio (SNR)—enabling high spatial resolution, improved tissue contrast, and efficient protocol performance. The scanner is installed in a dedicated imaging laboratory equipped for anesthesia, physiological monitoring, and animal welfare, supporting robust experimental planning and repeatable in-vivo imaging.
Purpose / Output
• Anatomical brain and body imaging in rat and mouse models (T1/T2)
• Advanced imaging: DWI, DTI/tractography, fMRI/rs-fMRI, perfusion, spectroscopy
• Contrast-enhanced imaging (DCE) and biodistribution assessments
• Parametric mapping: T1, T2, T2*
• Cardiac imaging with triggered protocols
• Sequence/application development and imaging-based evaluation of targeted therapy agents
Application Areas
• Neuroimaging: DTI, tractography, rs-fMRI, neurodegenerative disease models
• Oncology: tumor imaging, DCE, therapy response monitoring
• Metabolic/autoimmune models; diabetes, aging, stroke, depression
• Cardiac and abdominal imaging; musculoskeletal applications
• In-vivo/ex-vivo assessments in tissue engineering and biomaterials studies
• Multi-center studies and sequence/hardware/software development projects
Highlights
• High SNR and high resolution enabled by 7T field strength + dedicated small-animal bore/coils
• Strong gradients supporting diffusion-based protocols (DWI/DTI)
• Robust in-vivo workflow with isoflurane anesthesia, physiological monitoring, and heated animal beds
• Head holders enabling strong immobilization and, in suitable cases, brain imaging without respiratory triggering
Technical Specifications
| Feature | Value / Description |
|---|---|
| System / field strength | MRSolutions MRS*DRYMAG 7017 – 7 Tesla |
| Supported sample types | In-vivo, ex-vivo, and other samples (devices/chemicals, etc.) |
| Max RF coil inner diameter | 66.5 mm |
| Gradient strength | 600 mT/m |
| Rat/mouse RF coils | Dedicated Tx/Rx quadrature coils (rat brain, rat body, mouse body) |
| Surface receive coils | Available |
| Anesthesia | Isoflurane gas anesthesia system |
| Monitoring | SA Instruments Model 1030 MR-compatible (ECG, heart rate, respiration rate, body temperature) |
| Triggering | ECG and respiratory triggering |
| Animal beds | Dedicated heated beds (rat body, mouse body, rat brain, mouse brain) |
| Immobilization | Head holders for excellent fixation (enabling, when suitable, brain imaging without respiratory triggering) |
| Usage note | In operation |
Imaging Applications (Sequences/Protocols)
• T1- and T2-weighted imaging (brain, organs, tumors, etc.)
• Diffusion-weighted imaging (DWI)
• Diffusion tensor imaging (DTI) and tractography
• Contrast-enhanced imaging (DCE)
• T1, T2, T2* mapping
• Biodistribution studies (e.g., contrast-agent-linked targeted drugs using T1 maps)
• Resting-state fMRI (rs-fMRI)
• Perfusion imaging
• MR spectroscopy
• Cardiac imaging
• Multi-center studies
• Imaging hardware/software/sequence development
• Testing targeted therapy agents and imaging tracers/markers
Contact / Service Request
For service requests: you may email [email protected]. (Please specify the sample type, purpose, and preferred date range.)